IVM – In-Vitro Maturation

Another advanced assistive reproduction procedure that is said to cost $45000 less than a typical IVF procedure in the United States, IVM is now gaining momentum in India as a method of artificial conception. In-vitro maturation reduces a female patient’s exposure to fertility drugs which can lead to several complications. One of them being, ovarian hyper stimulation syndrome in women already suffering from PCOS.


IVM in practice is really simple: In this process, eggs are removed from the ovaries of the female patient when they are still immature and are thereafter fertilized in the laboratory. Another case when IVM is preferred over IVF is when clinical tests have proven that the causes of a couple’s infertility are associated with the male partner.


  • IVM is different from IVF in one main aspect that the eggs are immature before collected in IVM, while in IVF, mature eggs are collected. Three days of follicular stimulating hormone therapy is administered before the IVM treatment begins.
  • The collected eggs are put in an incubator for a couple of days in the laboratory using a special culture solution. When the eggs mature, they are fertilized with the donor sperm.
  • The resulting embryos are cultured and implanted in the uterus of the female patient. In IVM, fewer eggs are collected as compared to a typical IVF cycle but fewer complications are making it a sensible proposition amongst couples having an aversion to fertility drugs.


Females opting for IVM can save themselves from the prospect of cysts, abdominal pains, bloating, sickness and morbid obesity that usually occurs due to fertility drugs which cause OHSS  or Ovarian Hyper-stimulation Syndrome during an IVF cycle. No drugs need to be ingested before harvesting eggs for IVM, and therefore fertility specialists are now leaning towards IVM when it comes to assisted conception.

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